front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |review |
In experimental studies the most commonly
used survival analysis technique is likely to be the (non-parametric) Kaplan-Meier method
(1958). In epidemiology the most popular one is the (semi-parametric) Cox regression model
(1972). Very often in cancer clinical trials the primary comparison between treatment and
control groups is based on the Kaplan-Meier method. A secondary analysis with adjustment
for covariates based on the Cox regression model is then reported (see example 2). Example
1 and 3 used the Cox model and a parametric model, respectively. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Asso 1958; 53: 457-481. Cox DR. Regression models and life tables (with discussion). J Royal Stat Soc B 1972; 34: 187-220. |