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Using a Cox regression model with
treatment group as a single variable, the Stata command stcox group showes that Thiotepa is associated with a statistically insignificant reduction of hazard (HR=0.7; P=0.23). There is some baseline imbalance in pre-treatment number of tumors: the means are 1.9 and 2.3 in the control and Thiotepa groups, respectively. To adjust for this imbalance of risk factor, the following command is used: stcox group number Having adjusted for pre-treatment number of tumors, the treatment effect become stronger (HR=0.60; P=0.11). |