front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |31 |32 |33 |34 |35 |36 |37 |review

DHF/DSS in infants comprises the strongest evidence that IgG1 dengue antibodies enhance the severity of dengue disease. Enhanced viremias are produced in monkeys previously given polyclonal or monoclonal dengue antibodies at non-neutralizing concentrations (Halstead SB JID 140:527-533, 1979; Goncalvez et al PNAS 104:9422-7, 3007)