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The consistency
of CRP levels over time is quite good. In this analysis of CRP levels measured 5 years
apart in postinfarction patients in the CARE trial, the correlation coefficient over those
5 years for the hs-CRP was comparable, if not superior, to that of most of the other lipid
levels measured. These data have been corroborated elsewhere and again suggest that CRP
testing may have clinical utility. Reference:
Ridker PM, Rifai N, Pfeffer MA, Sacks F, Braunwald E, for the Cholesterol and Recurrent
Events (CARE) Investigators. Long-term effects of pravastatin on plasma concentration of
C-reactive protein. Circulation 1999;100:230-235.
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