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Biography |
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Dr. Ayman El-Shibiny is currently Professor of Biomedical Sciences, Director General for Research and Vice-Director of Accreditation Unit at the University of Science and Technology at Zewail City. El-Shibiny obtained his Doctor of Philosophy degree in Microbiology from The University of Nottingham, UK, in 2006. Prior to joining Zewail City, El-Shibiny was a postdoctoral fellow at a number of universities including University of Nottingham (UK), Cardiff University (UK), and The Evergreen State College (USA). As a microbiologist, El-Shibiny’s research interests cover a broad range of topics related to Food Safety and Human Health. He established the first Phage Therapy lab in Egypt at Zewail City. His main research area is Phage Therapy, and his current research interests include the therapeutic use of bacteriophages as a possible alternative to treat and control antibiotic-resistant pathogens in food, veterinary, and humans.
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Abstract |
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The novel bacteriophage approach to combat antibiotic-resistant pathogens |
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Excessive use of antibiotics in animal production led to a widespread acquisition of antibiotic-resistance (AR) in pathogenic and commensal bacteria which poses a substantial hazard to humans. The increase in numbers of antibiotic resistant pathogenic bacteria such as Salmonella, E. coli and Campylobacter has become a worldwide issue. The development of an alternative treatment to antibiotics has become one of the highest priorities worldwide due to the increase rate of resistance among all bacterial isolates according to the WHO statistics. Our research aims to use phage therapy as novel approaches to control bacterial infections. Phages cocktails are suitable for achieving this goal by using an innovative phage-delivery system that is developed recently in our laboratories. Although targeted pathogens may eventually develop resistance to selected phages, the phage cocktails can be easily reformulated to cope with any future resistance development. |
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